Lovastatin

Properties Simple | Detailed

Property	Value
Formula	C₂₄H₃₆O₅
IUPAC Name	[(1s,3r,7s,8s,8ar)-8-[2-[(2r,4r)-4-hydroxy-6-oxo-tetrahydropyran-2-yl]ethyl]-3,7-dimethyl-1,2,3,7,8,8a-hexahydronaphthalen-1-yl] (2s)-2-methylbutanoate
Molecular Mass	404.540 g·mol⁻¹
Heat of Formation	-1057.0 ± 16.7 kJ·mol⁻¹
Dipole Moment	5.80 ± 1.08 D
Volume	522.31 Å ³
Surface Area	403.42 Å ²
HOMO Energy	-8.78 ± 0.55 eV
LUMO Energy	0.10 ± eV
Point Group Symmetry	C₁
Synonyms	(1s,3r,7s,8s,8ar)-1,2,3,7,8,8a-hexahydro-3,7-dimethyl-8-(2-(2r,4r)-(tetrahydro-4-hydroxy-6-oxo-2h-pyran-2-yl)ethyl)-1-naphthalenyl (s)-2-methyl-butyrate (1s,3r,7s,8s,8ar)-8-{2-[(2r,4r)-4-hydroxy-6-oxotetrahydro-2h-pyran-2-yl]ethyl}-3,7-dimethyl-1,2,3,7,8,8a-hexahydronaphthalen-1-yl (2s)-2-methylbutanoate (1s-(1alpha(r),3alpha,7beta,8beta(2s,4s),8abeta))-2-methylbutanoic acid 1,2,3,7,8,8a-hexahydro-3,7-dimethyl-8-(2-(tetrahydro-4-hydroxy-6-oxo-2h-pyran-2-yl)ethyl)-1-naphthalenyl ester (2s)-2-methylbutanoic acid (1s,3r,7s,8s,8ar)-1,2,3,7,8,8a-hexahydro-3,7-dimethyl-8-[2-[(2r,4r)-tetrahydro-4-hydroxy-6-oxo-2h-pyran-2-yl]ethyl]-1-naphthalenyl ester (2s)-2-methylbutanoic acid [(1s,3r,7s,8s,8ar)-8-[2-[(2r,4r)-4-hydroxy-6-oxo-2-tetrahydropyranyl]ethyl]-3,7-dimethyl-1,2,3,7,8,8a-hexahydronaphthalen-1-yl] ester (2s)-2-methylbutyric acid [(1s,3r,7s,8s,8ar)-8-[2-[(2r,4r)-4-hydroxy-6-keto-tetrahydropyran-2-yl]ethyl]-3,7-dimethyl-1,2,3,7,8,8a-hexahydronaphthalen-1-yl] ester (s)-2-methyl-butyric acid (1s,3r,7s,8s,8ar)-8-[2-((3r,5r)-4-hydroxy-6-oxo-tetrahydro-pyran-2-yl)-ethyl]-3,7-dimethyl-1,2,3,7,8,8a-hexahydronaphthalen-1-yl ester (s)-2-methylbutyric acid, 8-ester with (4r,6r)-6-(2-((1s,2s,6r,8s,8ar)-1,2,6,7,8,8a-hexahydro-8-hydroxy-2,6-dimethyl-1-naphthyl)ethyl)tetrahydro-4-hydroxy-2h-pyran-2-one 1,2,6,7,8,8a-hexahydro-beta,delta-dihydroxy-2,6-dimethyl-8-(2-methyl-1-oxobutyoxy)-1-naphthaleneheptanoic acid delta-lactone 2beta,6alpha-dimethyl-8alpha-(2-methyl-1-oxobutoxy)-mevinic acid lactone 6-alpha-methylcompactin 6alpha-methylcompactin [(1s,3r,7s,8s,8ar)-8-[2-[(2r,4r)-4-hydroxy-6-oxo-oxan-2-yl]ethyl]-3,7-dimethyl-1,2,3,7,8,8a-hexahydronaphthalen-1-yl] (2s)-2-methylbutanoate [(1s,3r,7s,8s,8ar)-8-[2-[(2r,4r)-4-hydroxy-6-oxo-tetrahydropyran-2-yl]ethyl]-3,7-dimethyl-1,2,3,7,8,8a-hexahydronaphthalen-1-yl] (2s)-2-methylbutanoate acon0_000534 acon1_000390 altoprev artein bb_nc-1457 belvas bpbio1_000519 butanoic acid, 2-methyl-, (1s,3r,7s,8s,8ar)-1,2,3,7,8,8a-hexahydro-3,7-dimethyl-8-(2-(tetrahydro-4-hydroxy-6-oxo-2h-pyran-2-yl)ethyl)-1-naphthalenyl ester, (2s)- butanoic acid, 2-methyl-, 1,2,3,7,8,8a-hexahydro-3,7-dimethyl-8-(2-(tetrahydro-4-hydroxy-6-- oxo-2h-pyran-2-yl)ethyl)-1-naphthalenyl ester, (1s-(1alpha(r),3alpha,7beta,8beta(2s,4s),8abeta))- butanoic acid, 2-methyl-, 1,2,3,7,8,8a-hexahydro-3,7-dimethyl-8-(2-(tetrahydro-4-hydroxy-6-oxo-2h-pyran-2-yl)ethyl)-1-naphthalenyl ester, (1s-(1alpha(r),3alpha,7beta,8beta(2s,4s*),8abeta))- cholestra closterol colevix d00359 hipolip hipovastin l-154803 lestatin lipdip lipivas lipofren liposcler lovalip lovalord lovastatin (usp) lovastatina [spanish] lovastatinum [latin] lovasterol lovastin lozutin ls-46359 megxm0_000398 mevacor mevinacor mevinolin mevinolin from aspergillus sp. mevlor mk 803 mk-803 ml-530b monacolin k monakolin k msd 803 nergadan paschol rextat rodatin rovacor sivlor taucor tecnolip teroltrat
CAS Number(s)	74133-25-8 81739-26-6 75330-75-5 71949-96-7
InChIKey	PCZOHLXUXFIOCF-BXMDZJJMSA-N
QR Code	Generate QR Code
Links	PubChem Wikipedia ChemSpider
DOI	10.17614/Q4RX94916 10/f3d7q7
Downloads	Get JSON data Get MOL2 data Get SVG Image
Elements	H C O
	alkene hydrophilic alkyl carbonyl ester donor ring lactone