Dexamethasone

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Formula C22H29FO5
IUPAC Name (8s,9r,10s,11s,13s,14s,16r,17r)-9-fluoro-11,17-dihydroxy-17-(2-hydroxyacetyl)-10,13,16-trimethyl-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-3-one
Molecular Mass 392.461 g·mol−1
Heat of Formation -1095.8 ± 16.7 kJ·mol−1
Dipole Moment 2.93 ± 1.08 D
Volume 458.03 Å 3
Surface Area 350.59 Å 2
HOMO Energy -10.00 ± 0.55 eV
LUMO Energy -0.65 ± eV
Point Group Symmetry C1
Synonyms
  • (11beta,16alpha)-9-fluoro-11,17,21-trihydroxy-16-methylpregna-1,4-diene-3,20-dione
  • (11beta,16beta)-9-fluoro-11,17,21-trihydroxy-16-methylpregna-1,4-diene-3,20-dione
  • (3h)-dexamethasone
  • (8s,9r,10s,11s,13s,14s,16r,17r)-9-fluoro-11,17-dihydroxy-17-(2-hydroxy-1-oxoethyl)-10,13,16-trimethyl-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-3-one
  • (8s,9r,10s,11s,13s,14s,16r,17r)-9-fluoro-11,17-dihydroxy-17-(2-hydroxyacetyl)-10,13,16-trimethyl-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-3-one
  • (8s,9r,10s,11s,13s,14s,16r,17r)-9-fluoro-11,17-dihydroxy-17-(2-hydroxyethanoyl)-10,13,16-trimethyl-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-3-one
  • (8s,9r,10s,11s,13s,14s,16r,17r)-9-fluoro-17-glycoloyl-11,17-dihydroxy-10,13,16-trimethyl-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-3-one
  • .delta.(sup 1)-9-.alpha.-fluoro-16-.alpha.-methylcortisol
  • .gamma.corten
  • 1-dehydro-16-alpha-methyl-9-alpha-fluorohydrocortisone
  • 1-dehydro-16.alpha.-methyl-9.alpha.-fluorohydrocortisone
  • 1-dehydro-16alpha-methyl-9alpha-fluorohydrocortisone
  • 16-.alpha.-methyl-9-.alpha.-fluoro-1,4-pregnadiene-11-.beta.,17-.alpha.,21-triol-3,20-dione
  • 16-alpha-methyl-9-alpha-fluoro-1,4-pregnadiene-11-beta,17-alpha,21-triol-3,20-dione
  • 16-alpha-methyl-9-alpha-fluoro-1-dehydrocortisol
  • 16-alpha-methyl-9-alpha-fluoro-11-beta,17-alpha,21-trihydroxypregna-1,4-diene-3,20-dione
  • 16-alpha-methyl-9-alpha-fluoro-delta(sup 1)-hydrocortisone
  • 16-alpha-methyl-9-alpha-fluoro-delta1-hydrocortisone
  • 16-alpha-methyl-9-alpha-fluoroprednisolone
  • 16.alpha.-methyl-9.alpha.-fluoro-.delta.(sup1)-hydrocortisone
  • 16.alpha.-methyl-9.alpha.-fluoro-1-dehydrocortisol
  • 16.alpha.-methyl-9.alpha.-fluoro-11.beta.-17.alpha.-21-trihydroxypregna-1,4-diene-3,20-dione
  • 16.alpha.-methyl-9.alpha.-fluoroprednisolone
  • 16alpha-methyl-9alpha-fluoro-1-dehydrocortisol
  • 16alpha-methyl-9alpha-fluoro-delta(sup 1)-hydrocortisone
  • 16alpha-methyl-9alpha-fluoroprednisolone
  • 4-alpha-fluoro-16-alpha-methyl-11-beta,17,21-trihydroxypregna-1,4-diene-3,20-dione
  • 4.alpha.-fluoro-16.alpha.-methyl-11.beta.-17,21-trihydroxypregna-1,4-diene-3,20-dione
  • 9-alpha-fluoro-16-alpha-methyl-1,4-pregnadiene-11-beta,17-alpha,21-triol-3,20-dione
  • 9-alpha-fluoro-16-alpha-methylprednisolone
  • 9-fluoro-11-beta,17,21-trihydroxy-16-alpha-methylpregna-1,4-diene-3,20-dione
  • 9-fluoro-11.beta.,17,21-trihydroxy-16.alpha.-methylpregna-1,4-diene-3,20-dione
  • 9-fluoro-11beta,17,21-trihydroxy-16alpha-methylpregna-1,4-diene-3,20-dione
  • 9.alpha.-fluoro-11.beta.-17.alpha.- 21-trihydroxy-16.alpha.-methylpregna-1,4-diene-3,20-dione
  • 9.alpha.-fluoro-16.alpha.-methyl-1,4-pregnadiene-11.beta.-17-.alpha.-21-triol-3,20-dione
  • 9.alpha.-fluoro-16.alpha.-methyl-11.beta.,17.alpha.,21.beta.-trihydroxy-pregna-1,4-diene-3,20-dione
  • 9.alpha.-fluoro-16.alpha.-methylprednisolone
  • 9a-fluoro-16beta-methylprednisolone
  • 9alpha-fluoro-16alpha-methyl-11beta,17alpha,21-trihydroxy-1,4-pregnadiene-3,20-dione
  • 9alpha-fluoro-16alpha-methylprednisolone
  • aeroseb-d
  • aeroseb-dex
  • anaflogistico
  • aphtasolon
  • auxiron
  • azium
  • azium (veterinary)
  • bisu ds
  • calonat
  • corsone
  • cortisumman
  • d00292
  • decacortin
  • decaderm
  • decadron
  • decadron tablets, elixir
  • decagel
  • decalix
  • decasone
  • decaspray
  • dectancyl
  • dekacort
  • delta(sup 1)-9-alpha-fluoro-16-alpha-methylcortisol
  • delta1-9alpha-fluoro-16alpha-methylcortisol
  • deltafluorene
  • dergramin
  • deronil
  • desadrene
  • desametasone
  • desametasone [dcit]
  • desamethasone
  • desameton
  • deseronil
  • dex-ide
  • dexa mamallet
  • dexa-cortidelt
  • dexa-cortisyl
  • dexa-scheroson
  • dexa-sine
  • dexacort
  • dexacortal
  • dexacortin
  • dexadeltone
  • dexafarma
  • dexalona
  • dexameth
  • dexamethasone (jp15/usp/inn)
  • dexamethasone [ban:inn:jan]
  • dexamethasone alcohol
  • dexamethazone
  • dexapolcort
  • dexaprol
  • dexason
  • dexasone
  • dexinolon
  • dexinoral
  • dexone
  • dextelan
  • dezone
  • dinormon
  • drg-0013
  • dxm
  • dxms
  • fluormethylprednisolone
  • fluormone
  • fluorocort
  • fortecortin
  • gammacorten
  • hexadecadrol
  • hexadrol
  • hexadrol elixir
  • hexadrol tablets
  • hl-dex
  • isopto-dex
  • lokalison f
  • loverine
  • luxazone
  • maxidex
  • mediamethasone
  • mexidex
  • millicorten
  • mk 125
  • molmap_000018
  • naquasone (veterinary)
  • ocu-trol
  • oradexon
  • pet derm iii
  • policort
  • prednisolon f
  • prednisolone f
  • prednisolone, 9.alpha.-fluoro-16.alpha.-methyl-
  • prednisolone, 9alpha-fluoro-16alpha-methyl-
  • pregna-1,4-diene-3,20-dione, 9-fluoro-11,17,21-trihydroxy-16-methyl-, (11.beta.,16.alpha.)-
  • pregna-1,4-diene-3,20-dione, 9-fluoro-11,17,21-trihydroxy-16-methyl-, (11beta,16alpha)-
  • pregna-1,4-diene-3,20-dione, 9-fluoro-11.beta.,17,21-trihydroxy-16.alpha.-methyl-
  • pregna-1,4-diene-3,20-dione, 9-fluoro-11beta,17,21-trihydroxy-16alpha-methyl-
  • prodex
  • sgcut00126
  • sk-dexamethasone
  • smp1_000092
  • spoloven
  • sunia sol d
  • superprednol
  • to_000038
  • tobradex
  • visumetazone
CAS Number(s)
  • 137098-19-2
  • 8054-59-9
  • 50-02-2
  • 23495-06-9
InChIKey UREBDLICKHMUKA-CXSFZGCWSA-N
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